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Nithya, K.
- Growth Studies of Colletotrichum gloeosporioides (Penz.) Sacc. - a Taxol Producing Endophytic Fungus from Plumeria acutifolia
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Authors
K. Nithya
1,
J. Muthumary
1
Affiliations
1 Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai – 600 025, IN
1 Centre for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai – 600 025, IN
Source
Indian Journal of Science and Technology, Vol 2, No 11 (2009), Pagination: 14-19Abstract
Plumeria acutifolia Poiret (Apocynaceae) is grown as an ornamental plant in India, Indonesia, Philippines and South Africa. Various species of this plant are used as medicine to cure many diseases and also as antipsychotic, diuretic, or antitumour agent. Some iridoids and triterpenoids obtained from this plant are reported to have algicidal, antibacterial and cytotoxic activity. Some species of Plumeria are also used for the cure of rheumatism, diarrhoea, blennorhea, venereal disease and leprosy. This study investigates the taxol production by Colletotrichum gloeosporioides, an endophytic fungus of Plumeria acutifolia. The presence of Taxol was confirmed through TLC, UV and IR spectroscopic methods. The amount of taxol was quantified through HPLC analysis. This is the first report that a coelomyceteous fungus producing taxol from this plant.Keywords
Taxol, Plumeria acutifolia/I>, Colletotrichum gloeosporioides, Endophytic Fungi, CoelomycetesFull Text
References
- Arnold AE, Maynard Z, Gilbert GS, Coley PD and Kursar TA (2000) Are tropical fungal endophytes hyperdiverse? Ecology Letters. 3, 267-274.
- Bhuvaneswari V and Muthumary J (2005) Diversity and seasonal influence of fungal endophytes in five medicinal plant species. Kavaka. 33, 39-55.
- Cardellina JH (1991) HPLC Separation of taxol and cephalomannine. J. Chromatogr. 14, 659-665.
- Dobhal MP, Guolin Li, Amy Gryshuk, Andrew Graham, Atul K. Bhatanagar, Sirajud D. Khaja, Yogesh C. Joshi, Sharma MC, Allan Oseroff and Ravindra K. Pandey (2004) Structural modifications of plumieride isolated from Plumeria bicolor and the effect of these modifications on in vitro. 69, 6165-6170.
- Ebenezer P, Murugan M and Muthumary J (2002) Effect of chemical environment on growth and sporulation in Pestalotiopsis spp. Indian J. Microbiol. 42, 303-307.
- Feng Xu, Wenyi Tao, Long Cheng and Lijia Guo (2006) Strain improvement and optimization of the media of taxol-producing fungus Fusarium maire. Biochemical Engineering Journal. Vol 31, 67-73.
- Ganga Devi V and Muthumary J (2008) Isolation of Colletotrichum gloeosporioides, a novel endophytic taxol-producing fungus from the leaves of a medicinal plant, Justicia gendarussa. Mycolog. Balc. 5, 1-4.
- Gangadevi V and Muthumary J (2007b) Endophytic fungal diversity from young, mature and senescent leaves of Ocimum basilicum L. with special reference to Taxol production. Indian J. Sci. Technol. 1(1), 1-12. Domain site: http://www.indjst.org
- Gangadevi V and Muthumary J (2007a) Preliminary studies on cytotoxic effect of fungal taxol on cancer cell line. Af. J. Biotech. 6 (12), 1382-1386.
- Gangadevi V and Muthumary J (2008a) A simple and rapid method for the determination of taxol produced by fungal endophytes from medicinal plants using high performance thin layer chromatography. Chin.J. Chrom. 26 (1), 50-55.
- Gangadevi V and Muthumary J (2008b) Taxol, an anticancer drug produced by an endophytic fungus Bartalinia robillardoides, Tassi, isolated from a medicinal plant, Aegle marmelos correa ex Roxb. W. J. Microbiol. Biotechnol. 24, 717-724.
- Gangadevi V, Sethumeenal S, Yogeswari S and Rani G (2008) Screening endophytic fungi isolated from a medicinal plant, Acalypha indica L. for antibacterial activity. Indian J. Sci. Technol. 1(5), 1-6. Domain site: http://www.indjst.org.
- Guo B, Wang X, Sun X and Tang K (2008) Bioactive natural products from endophytes: A review. App. Biochem. Microbio. 44 (2), 136-142.
- Guo BH, Kai GY, Jin HB and Tang KX (2006) Taxol synthesis. Af. J. Biotechnol. 5 (1), 15-20.
- Gupta RS, Bhatnagar AK, Joshi YC, Sharma R and Sharma A (2004) Effects of Plumieride, an iridoid on spermatogenesis in male albino rats. Phytomedicine. 11, 169-174.
- Ji Yuan, Bl. Jian- Nan, Yan Bing and ZHU Xu- Dong (2006) Taxol producing fungi: a new approach to industrial production of Taxol. Chin. J of Biotechnology 22, (1), 1-6.
- Jones WB, Schneider J and Shapiro F (1996) Treatment of resistant gestational Chorlocarcinoma with Taxol: A report of two cases. Gynecol. Oncol. 61(1), 126-130.
- Kwon K, Yoo JL, Lee JH and Hyun Jo (1998) Enhancement of Taxol production by in situ recovery of product. Process Biochem. 33, 701-707.
- Lu Hong, Wen Xin Zou, Jun Cai Meng, Jun Hu and Ren Xiang Tan (2000) New bioactive metabolites produced by Colletotrichum sp., an endophytic fungus in Artemisia annua. Plant Science. 151, 67-73.
- Muthumary J and Sashirekha S (2007) Detection of Taxol, an anticancer drug, from selected Coelomycetous fungi. Indian J. Sci. Technol. 1(1), 1-10. Domain site: http://www.indjst.org
- Owen NL and Hundley N (2004) Biodiversity of Marine derived fungi and identification of their metabolites. Sci. Prog. 87, 79-99.
- Pandi M, Manikandan R and Muthumary J (2009) Anticancer activity of fungal taxol from Botryodiopolidia theobromae pat., an endophytic fungus, against 7,12 dimethyl benz(a) anthracene (DMBA)– induced mammary gland carcinogenesis in sprague dawley rats. Bio Medicine & Pharmacotherapy. doi: 10.1016/j.biopha.2009.03.001.
- Pinkerton R and Strobel G (1976) Serinol as an activator of toxin production in attenuated cultures of H. sacchari. Proc. Nat. Acad. Sci.USA 73, 4007-4011.
- Puldduinen JO, Elomaa L and Joensu Hetsal (1996) Paclitaxel– induced apoptotic changes followed by tielapse video microscopy in cell lines established from head and neck cancer. J.Can Res. & Clin. Oncol. 22(4), 214-218.
- Senthil Kumaran Rangarajulu, John Paul Muthumary and Byung Ki Hur (2008) Taxol from Phyllosticta citricarpa, a leaf spot fungus of the Angiosperm Citrus medica. J. Biosci. Bioengin. 106 (1) 103-106.
- Stierle A, Strobel GA and Stierle D (1993) Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific Yew. Science. 260, 214-216.
- Strobel G and Daisy B (2003) Bioprospecting for microbial endophytes and natural products Microbiol. Mol. Bio. Rev. 67, 491-502.
- Strobel GA, Hess WM, Ford E, Sidhu RS and Yang X(1996b) Taxol from fungal endophytes and the issue of biodiversity. J. Ind. Microbiol. 17, 412-423.
- Strobel GA, Yang X, Sears J, Kramer R, Sidhu RS andHess WM (1996a) Taxol from Pestalotiopsis microscpora, an endophytic fungus of Taxus wallachiana. Microbiol. 142, 435-440.
- Van der Heijden R, Jacobs DI, Snoeijer W, Hallard D and Verpoorte R (2004) The catharanthus alkaloids: Pharmacognosy and biotechnology. Curr. Med. Chem. 11 (5) 607- 628.
- Wani MC, Taylor HL, Wall ME et al. (1971) Plant antitumor agents VI: The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. J.Am.Chem.Soc. 93, 2325– 2327.
- Woo HL, Swenerton KD and Hoskins PJ (1996) Taxol is active in platinum resistant endometrial adenocarcinoma. Ann. J. Clin. Oncol. 19(3), 290-291.
- Zhou DP and Ping Wx (2003) Anticancer taxol produced by microbiology fermentation. Chinese Science & Technol. Publ. House.